Description: JWH 018 is a synthetic cannabinoid (CB) that potently activates the central CB1 and peripheral CB2 receptors (Ki = 9.0 and 2.94 nM, respectively). This cannabimimetic compound has frequently been found in herbal blends. JWH 424 is an 8-bromonaphthyl derivative of JWH 018 which shows a reduced selectivity for CB1 over CB2 (Ki = 20.9 and 5.4 nM, respectively).

Name: JWH-424
CAS#: 1366068-04-3
Chemical Formula: C24H22BrNO
Exact Mass: 419.0885
Molecular Weight: 420.35
Elemental Analysis: C, 68.58; H, 5.28; Br, 19.01; N, 3.33; O, 3.81

Synonym: JWH-424; JWH 424; JWH424;

IUPAC/Chemical Name: (8-bromonaphthalen-1-yl)(1-pentyl-1H-indol-3-yl)methanone

InChi Key: QXZYVJRMQVOOEQ-UHFFFAOYSA-N

InChi Code: InChI=1S/C24H22BrNO/c1-2-3-6-15-26-16-20(18-11-4-5-14-22(18)26)24(27)19-12-7-9-17-10-8-13-21(25)23(17)19/h4-5,7-14,16H,2-3,6,15H2,1H3

SMILES Code: O=C(C1=CN(CCCCC)C2=C1C=CC=C2)C3=C4C(Br)=CC=CC4=CC=C3

Appearance: Solid powder

Purity: >98% (or refer to the Certificate of Analysis)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility: Soluble in DMSO

Shelf Life: >2 years if stored properly

Drug Formulation: This drug may be formulated in DMSO

Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code: 2934.99.9001