Description: GNF6231 is a novel WNT inhibitor, averting WNT pathway activation by blocking secretion of all WNT ligands.

Name: GNF6231
CAS#: 1243245-18-2
Chemical Formula: C24H25FN6O2
Exact Mass: 448.2023
Molecular Weight: 448.5024
Elemental Analysis: C, 64.27; H, 5.62; F, 4.24; N, 18.74; O, 7.13

Synonym: GNF6231; GNF-6231; GNF 6231

IUPAC/Chemical Name: N-[5-(4-Acetylpiperazin-1-yl)pyridin-2-yl]-2-[6-(2-fluoropyridin-4-yl)-5-methylpyridin-3-yl]acetamide

InChi Key: AXXNRMISICMFNS-UHFFFAOYSA-N

InChi Code: InChI=1S/C24H25FN6O2/c1-16-11-18(14-28-24(16)19-5-6-26-21(25)13-19)12-23(33)29-22-4-3-20(15-27-22)31-9-7-30(8-10-31)17(2)32/h3-6,11,13-15H,7-10,12H2,1-2H3,(H,27,29,33)

SMILES Code: O=C(NC1=NC=C(N2CCN(C(C)=O)CC2)C=C1)CC3=CC(C)=C(C4=CC(F)=NC=C4)N=C3

Appearance: Solid powder

Purity: >98% (or refer to the Certificate of Analysis)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility: Soluble in DMSO

Shelf Life: >3 years if stored properly

Drug Formulation: This drug may be formulated in DMSO

Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code: 2934.99.9001