Epipregnanolone-北京百奥创新科技有限公司

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Epipregnanolone

品牌：MedKoo

产地：美国

货号：464820

cas：128-21-2

发布日期： 2022-07-20
更新日期： 2024-08-12

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产地	美国
品牌	MedKoo
货号	464820
用途	This product is for research use only, not for human or veterinary use.
包装规格	5.0mg; 10.0mg; 25.0mg; 50.0mg; 100.0mg; 200.0mg; 500.0mg; 1.0g;
CAS编号	128-21-2
纯度	>98%%
是否进口	是

Description: Epipregnanolone is a neurosteroid and an active metabolite of the steroid hormone pregnenolone. It is enzymatically formed from prognenolone via the intermediates progesterone and 5β-dihydroprogesterone in the placenta. Epipregnanolone inhibits spontaneous contractions in myometrial strips isolated from at-term pregnant women (IC50 = 156 μM). Epipregnanolone (10 and 20 mg/kg) decreases operant alcohol self-administration in rats. Maternal plasma levels of epipregnanolone increase over the duration of pregnancy.

Synonym: Epipregnanolone; NSC 21450; NSC21450; NSC-21450; 5β-Pregnan-3β-ol-20-one;

IUPAC/Chemical Name: 1-((3S,5R,8R,9S,10S,13S,14S,17S)-3-hydroxy-10,13-dimethylhexadecahydro-1H-cyclopenta[a]phenanthren-17-yl)ethan-1-one

InChi Key: AURFZBICLPNKBZ-GRWISUQFSA-N

InChi Code: InChI=1S/C21H34O2/c1-13(22)17-6-7-18-16-5-4-14-12-15(23)8-10-20(14,2)19(16)9-11-21(17,18)3/h14-19,23H,4-12H2,1-3H3/t14-,15+,16+,17-,18+,19+,20+,21-/m1/s1

SMILES Code: C[C@@]12[C@@]3([C@]([H])([C@]4([C@]([C@@H](C(C)=O)CC4)(C)CC3)[H])CC[C@@]1(C[C@@H](O)CC2)[H])[H]

Appearance: Solid powder

Purity: >98% (or refer to the Certificate of Analysis)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility: To be determined

Shelf Life: >2 years if stored properly

Drug Formulation: To be determined

Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code: 2934.99.9001