Description: Dicentrine, (-)- is an aporphinic alkaloid found in several plant species, mainly from Lauraceae family, which showed significant antinociceptive activity in an acute model of visceral pain in mice. It has also been shown to reduce spontaneous nociception and attenuating mechanical and cold hypersensitivity, probably via a TRPA1-dependent mechanism.

Name: Dicentrine, (-)-
CAS#: 28832-07-7
Chemical Formula: C20H21NO4
Exact Mass: 339.1471
Molecular Weight: 339.39
Elemental Analysis: C, 70.78; H, 6.24; N, 4.13; O, 18.86

Synonym: Dicentrine, (-)-; L-Dicentrine; NSC-251699; NSC 251699; NSC251699;

IUPAC/Chemical Name: (R)-10,11-dimethoxy-7-methyl-6,7,7a,8-tetrahydro-5H-[1,3]dioxolo[4',5':4,5]benzo[1,2,3-de]benzo[g]quinoline

InChi Key: YJWBWQWUHVXPNC-CQSZACIVSA-N

InChi Code: InChI=1S/C20H21NO4/c1-21-5-4-11-7-17-20(25-10-24-17)19-13-9-16(23-3)15(22-2)8-12(13)6-14(21)18(11)19/h7-9,14H,4-6,10H2,1-3H3/t14-/m1/s1

SMILES Code: CN1CCC(C2=C3C4=CC(OC)=C(OC)C=C4C[C@@]12[H])=CC5=C3OCO5

Appearance: Solid powder

Purity: >98% (or refer to the Certificate of Analysis)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility: Soluble in DMSO

Shelf Life: >2 years if stored properly

Drug Formulation: This drug may be formulated in DMSO

Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code: 2934.99.9001