Desoximetasone-北京百奥创新科技有限公司

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Desoximetasone

品牌：MedKoo

产地：美国

货号：317590

cas：382-67-2

发布日期： 2022-07-20
更新日期： 2024-08-12

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产地	美国
品牌	MedKoo
货号	317590
用途	This product is for research use only, not for human or veterinary use.
包装规格	1.0g; 5.0g; 10.0g; 20.0g; 50.0g; 100.0g;
CAS编号	382-67-2
纯度	>98%%
是否进口	是

Description: Desoximetasone is a medication belonging to the family of medications known as topical corticosteroids. It is used for the relief of various skin conditions, including rashes. It helps to reduce redness, itching, and irritation. Desoximetasone is a synthetic corticosteroid, a class of primarily synthetic steroids used as anti-inflammatory and anti-pruritic agents. Desoximetasone activates specific intracellular receptors, which bind to distinct sites on DNA to modify gene transcription. This results in an induction of the synthesis of anti-inflammatory proteins and suppression of the synthesis of inflammatory mediators. This leads to an overall reduction in chronic inflammation and autoimmune reactions. Desoximetasone is indicated for the relief of the inflammatory and pruritic manifestations of corticosteroid-responsive dermatoses.

Synonym: A 41-304; A 41304; A-41-304; Desoximetasone; Desoximetasona; Desoximetasonum; Desoxymethasone; Flubason; baril; R 2113; Stiedex; Topicort; Topicort LP; Topisolon.

IUPAC/Chemical Name: (8S,9R,10S,11S,13S,14S,16R,17S)-9-fluoro-11-hydroxy-17-(2-hydroxyacetyl)-10,13,16-trimethyl-6,7,8,9,10,11,12,13,14,15,16,17-dodecahydro-3H-cyclopenta[a]phenanthren-3-one

InChi Key: VWVSBHGCDBMOOT-IIEHVVJPSA-N

InChi Code: InChI=1S/C22H29FO4/c1-12-8-16-15-5-4-13-9-14(25)6-7-21(13,3)22(15,23)18(27)10-20(16,2)19(12)17(26)11-24/h6-7,9,12,15-16,18-19,24,27H,4-5,8,10-11H2,1-3H3/t12-,15+,16+,18+,19-,20+,21+,22+/m1/s1

SMILES Code: [C@@H]12[C@@]([C@@]3(C(=CC(=O)C=C3)CC2)C)([C@H](C[C@]2([C@H]1C[C@H]([C@@H]2C(=O)CO)C)C)O)F

Appearance: Solid powder

Purity: >98% (or refer to the Certificate of Analysis)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility: Soluble in DMSO, not in water

Shelf Life: >2 years if stored properly

Drug Formulation: This drug may be formulated in DMSO

Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code: 2934.99.9001