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AST487
- 品牌：MedKoo
- 产地：美国
- 货号：406211
- cas：630124-46-8
- 发布日期： 2022-07-20
- 更新日期： 2024-08-12
产品详请
| 产地 | 美国 |
| 品牌 | MedKoo |
| 货号 | 406211 |
| 用途 | This product is for research use only, not for human or veterinary use. |
| 包装规格 | 10.0mg; 25.0mg; 50.0mg; 100.0mg; 200.0mg; 500.0mg; 1.0g; 2.0g; |
| CAS编号 | 630124-46-8 |
| 纯度 | >98%% |
| 是否进口 | 是 |
中文名称:化合物AST 487
中文别名:RET激酶抑制剂(AST 487)
CAS No:630124-46-8
EINECS号：205-525-8
分子式:C26H30F3N7O2
沸点:563.1±50.0 °C(Predicted)
密度:1.341±0.06 g/cm3(Predicted)
用途:AST-487 is an inhibitor of RET (IC50 = 0.88 μM), FLT3 (Ki = 0.52 μM), KDR (IC50 = 0.17 μM), c-Abl (IC50 = 0.02 μM), and c-Kit (IC50 = 0.5 μM). It has been shown to inhibit RET autophosphorylation and activation of downstream effectors and to prevent the growth of human thyroid cancer cell lines..
中文别名:RET激酶抑制剂(AST 487)
CAS No:630124-46-8
EINECS号：205-525-8
分子式:C26H30F3N7O2
沸点:563.1±50.0 °C(Predicted)
密度:1.341±0.06 g/cm3(Predicted)
用途:AST-487 is an inhibitor of RET (IC50 = 0.88 μM), FLT3 (Ki = 0.52 μM), KDR (IC50 = 0.17 μM), c-Abl (IC50 = 0.02 μM), and c-Kit (IC50 = 0.5 μM). It has been shown to inhibit RET autophosphorylation and activation of downstream effectors and to prevent the growth of human thyroid cancer cell lines..
